No. 21 F/W 16 is a runway show by the brand No. 21, designed by Alessandro Dell'Acqua. It took place on February 24, 2016, during Milan Fashion Week F/W 16 Women's. The casting director for the show was Rosalba Troiano, and it featured a cast of 33 models. The show was opened by Marjan Jonkman and closed by Lorelle Rayner.